Saturday 10 August 2013

Scientists Discover Gene That Restricts Tumours

Scientists at the Jawaharlal Nehru University's School of Biotechnology appointees in the third week of January 2013 that they limit the SCO2 gene that potential qualities of tumors. SCO2 scientists suggested that this gene may therefore be used for the treatment of various types of cancer.

Now p53 gene was considered the proteins that block access to the tumors and prevents thus preventing cancer. But according to the combined research carried out by scientists at JNU School of Biotechnology and Ohio State University Medical Center, as well as other universities, p53 gene SCO2 gene uses too much with this tumor-suppressing quality.

In the study of the scientific SCO2 protein injected that is encoded in SCO2-gene, in the colon as well as the mammary tumor xenografts in mice. The result was constant decay of tumors. When SCO2 was combined with anticancer drugs such as tamoxifen and cisplatin, success rate hypoxic respiratory failure tumor regression was 85 percent in four weeks.

Really, SCO2 is responsible for enhancing the production of reactive oxygen species (ROS), which, in turn, activates the apoptosis signal regulating kinase 1 (question 1). Apoptosis signal regulating kinase 1 (question 1), then that happens, the growth of tumors. ROS is a kind of unstable molecule in which oxygen, which in turn leads to easy reaction with the other molecule in the cell. Building of ROS in the cells, can lead to damaged DNA, RNA, and proteins, ultimately fatal. However SCO2 promote positive result of ROS cause, is activated cell death and thus shrink the tumors.

However, scientists have also made ​​it clear to translate these findings to the real treatment or therapy Lane will take time. But it is still very important step in understanding the causes of cancer agency process.  Scientists declare the importance of cancer cell metabolism and control all relevant genes, but they need to be understood and discovered. However, with the future of advanced therapies and treatment of cancer will not remain a deadly disease.

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